Aberrant Methylation in Hematological Malignancies
نویسندگان
چکیده
منابع مشابه
Aberrant methylation of Reprimo in human malignancies.
Reprimo is a new candidate mediator of p53-mediated cell cycle arrest at the G2 phase. Loss of Reprimo gene expression accompanied by its promoter methylation was identified in pancreatic and lung cancers. Our aim was to examine the methylation status of Reprimo in a broad range of cancers. We examined Reprimo expression by RT-PCR and the DNA methylation status of the Reprimo promoter by MSP in...
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ژورنال
عنوان ژورنال: Translational Medicine
سال: 2012
ISSN: 2161-1025
DOI: 10.4172/2161-1025.s1-004